Basics of Alzheimer’s Disease and Dementia

Alzheimer’s Disease (AD) is a disorder that causes degeneration of the cells in brain and it main cause dementia, which characterized by decline Independence an individual’s daily activities. AD considered multifactorial disease. Two hypotheses have been proposed as AD. The cholinergic hypothesis amyloid hypothesis. In addition, several risk factors implicated this disease, including aging, genetic factors, head trauma, vascular infections, environmental factors. Currently, there are only two classes drugs approved for treatment AD, cholinesterase enzyme inhibitors N-Methyl-D-Aspartic Acid (NMDA) antagonists, not associated with symptoms or Prevent. Today, research focused on understanding pathology targeting multiple mechanisms such alteration course. This review describes currently available future theories development new treatments Disease-Modifying Therapies (DMTs), chaperones, natural products.